Oji has similar problems, overall. We never had him very overtly bite at us; but thinking back, yes, he used to paw and mouth at my legs as I left (for a phase, we used to leave him alone in the house when he was a year or so old, but he lost that privilege probably for life). I know that when I tie him out to a tree or something at a park or some such place so I can separate myself from him for a few moments, say at a park and walk several paces away, he may paw and bite at my legs as I leave. He then barks aggressively, which is his default bark.
Yes, we had major peeing issues when left alone. We crate trained since early on, and he would always pee and poo in his crate when left.
For a phase, we used to leave him loose in the house when we'd leave, and he'd bark like a maniac, but the only thing disturbed was the front rug was all bunched up. The day he lost his freedom for good, my wife and I took our daughter to a birthday party and we had lunch out. It rained and mildly stormed during that time. We came home to pee and destruction, very thankfully, located mainly in one bathroom where he chose to freak out. Yes, he has storm anxiety too.

So, he is always in his crate every time I leave the house. It's a major hassle, especially since nowadays I also muzzle him in the crate because over the years he has chewed his crate to the brink of needing replaced (NOTE: It may be a safety hazard to leave a dog muzzled in a crate).
But let me share with you the situation surrounding the glorious day he finally stopped peeing in his crate:
For this particular Doberman, comfort is paramount. Yeah, real tough guard dog here. He melts in the warm sun. It was one of the very first hot days of the year, and I switched from the wire crate on the main floor where it was warm back to his plastic crate in the basement where it is cool, darkish and sort of cozy in a way. He had been out for a hot walk, and I then crated him in this spot and haleluia, when I came back home, no pee!!! He did not relieve himself in the crate after that day! No, I cannot leave any sort of blanket or cushion or anything in his crate with him though. He will destroy it and possibly ingest it and have a dangerous or life-threatening internal situation result.
So, I would seek to find a safe crating situation for your Dobe that suits her individual needs.