This is from 2018, but I think written in a way that is easy to understand. I'm a nerd about genetics but use to be because I loved the science of what produced the best Thoroughbreds, and certain colors, and how Bengal cats came to be. Not because my favorite breed of dog is literally dying for our efforts of purity. Here's a fairly short article that explains it all.
www.popsci.com
Scientists have identified a gene that's killing purebred dogs. Does that even matter?
Bull terrier owners might feel some sense of relief upon hearing that a team of international researchers have identified a genetic mutation behind lethal acrodermatitis. Baby bull terriers with LAD often die before their first birthday. But at this point, we can’t really do much about it.
www.popsci.com